Power and loyalty defined by proximity to influential relations

This paper examines a simple definition of power as a composite centrality being the composition of eigenvector centrality and edge betweeness. Various centralities related to the composition are compared on social and collaboration networks. A derived defection score for social fission scenarios is introduced and is demonstrated in Zachary’s Karate club to predict the sole defection in terms of network measures rather than psychological factors. In a network of political power in Mexico across various periods, the two definitions of power serve to shed light on a political power transition between two groups

Globalization, international law, and emerging infectious diseases.

The global nature of the threat posed by new and reemerging infectious diseases will require international cooperation in identifying, controlling, and preventing these diseases. Because of this need for international cooperation, international law will certainly play a role in the global strategy for the control of emerging diseases. Recognizing this fact, the World Health Organization has already proposed revising the International Health Regulations. This article examines some basic problems that the global campaign against emerging infectious diseases might face in applying international law to facilitate international cooperation. The international legal component of the global control strategy for these diseases needs careful attention because of problems inherent in international law, especially as it applies to emerging infections issues

Introducing random walk measures to space syntax

We introduce Random Walk Closeness (RWC) to the space syntax computational paradigm. Random walks are stochastic processes in which an unbiased walker traverses a network purely based on his current location. Random walks have been used by space syntax in an agent based scenario, where results are simulation based. Here, the results are mathematical based, i.e. RWC is derived from access times, which are the average number of steps it takes to walk between locations. Results suggest an improvement in correlating pedestrian movement over Integration, RA and network Closeness

Investigation of characteristics of feed system instabilities

The relationship between the structural and feed system natural frequencies in structure-propulsion system coupled longitudinal oscillations (pogo) is investigated. The feed system frequencies are usually very dependent upon the compressibility (compliance) of cavitation bubbles that exist to some extent in all operating turbopumps. This document includes: a complete review of cavitation mechanisms; development of a turbopump cavitation compliance model; an accumulation and analysis of all available cavitation compliance test data; and a correlation of empirical-analytical results. The analytical model is based on the analysis of flow relative to a set of cascaded blades, having any described shape, and assumes phase changes occur under conditions of isentropic equilibrium. Analytical cavitation compliance predictions for the J-2 LOX, F-1 LOX, H-1 LOX and LR87 oxidizer turbopump inducers do not compare favorably with test data. The model predicts much less cavitation than is derived from the test data. This implies that mechanisms other than blade cavitation contribute significantly to the total amount of turbopump cavitation

Spin-torque switching: Fokker-Planck rate calculation

We describe a new approach to understanding and calculating magnetization switching rates and noise in the recently observed phenomenon of "spin-torque switching". In this phenomenon, which has possible applications to information storage, a large current passing from a pinned ferromagnetic (FM) layer to a free FM layer switches the free layer. Our main result is that the spin-torque effect increases the Arrhenius factor $\exp(-E/kT)$ in the switching rate, not by lowering the barrier $E$, but by raising the effective spin temperature $T$. To calculate this effect quantitatively, we extend Kramers' 1940 treatment of reaction rates, deriving and solving a Fokker-Planck equation for the energy distribution including a current-induced spin torque of the Slonczewski type. This method can be used to calculate slow switching rates without long-time simulations; in this Letter we calculate rates for telegraph noise that are in good qualitative agreement with recent experiments. The method also allows the calculation of current-induced magnetic noise in CPP (current perpendicular to plane) spin valve read heads.Comment: 11 pages, 8 figures, 1 appendix Original version in Nature format, replaced by Phys. Rev. Letters format. No substantive change

Virus Sharing, Genetic Sequencing, and Global Health Security

The WHO’s Pandemic Influenza Preparedness (PIP) Framework was a milestone global agreement designed to promote the international sharing of biological samples to develop vaccines, while that ensuring poorer countries would have access to those vaccines. Since the PIP Framework was negotiated, scientists have developed the capacity to use genetic sequencing data (GSD) to develop synthetic viruses rapidly for product development of life-saving technologies in a time-sensitive global emergency—threatening to unravel the Framework. Access to GSD may also have major implications for biosecurity, biosafety, and intellectual property (IP). By rendering the physical transfer of viruses antiquated, GSD may also undermine the effectiveness of the PIP Framework itself, with disproportionate impacts on poorer countries. We examine the changes that need to be made to the PIP Framework to address the growing likelihood that GSD might be shared instead of physical virus samples. We also propose that the international community harness this opportunity to expand the scope of the PIP Framework beyond only influenza viruses with pandemic potential. In light of non-influenza pandemic threats such as the Middle East Respiratory Syndrome (MERS) and Ebola, we call for an international agreement on the sharing of the benefits of research – such as vaccines and treatments – for other infectious diseases to ensure not only a more secure and healthy world, but also a more just world, for humanity

A contribution to the second neighborhood problem

Seymour's Second Neighborhood Conjecture asserts that every digraph (without digons) has a vertex whose first out-neighborhood is at most as large as its second out-neighborhood. It is proved for tournaments, tournaments missing a matching and tournaments missing a generalized star. We prove this conjecture for classes of digraphs whose missing graph is a comb, a complete graph minus 2 independent edges, or a complete graph minus the edges of a cycle of length 5

A Public Health Emergency of International Concern? Response to a Proposal to Apply the International Health Regulations to Antimicrobial Resistance

Adam Kamradt-Scott critiques a proposal to apply the International Health Regulations (IHR) to the global health threat of antimicrobial resistance